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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEMA6D
All Species:
22.42
Human Site:
Y472
Identified Species:
49.33
UniProt:
Q8NFY4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFY4
NP_065909.1
1073
119872
Y472
L
L
E
E
I
E
A
Y
N
H
A
K
C
S
A
Chimpanzee
Pan troglodytes
XP_523068
1073
119853
Y472
L
L
E
E
I
E
A
Y
N
H
A
K
C
S
A
Rhesus Macaque
Macaca mulatta
XP_001112236
1073
119718
Y472
L
L
E
E
I
E
A
Y
N
H
A
K
C
S
A
Dog
Lupus familis
XP_535466
1073
119672
Y472
L
L
E
E
I
E
A
Y
N
Q
A
K
C
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q76KF0
1073
119796
Y472
L
L
E
E
I
E
A
Y
N
P
A
K
C
S
A
Rat
Rattus norvegicus
O70141
887
95734
F303
P
G
D
S
H
F
Y
F
N
V
L
Q
A
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90663
761
87282
P178
C
P
F
D
P
Q
Q
P
F
A
S
V
M
A
D
Frog
Xenopus laevis
NP_001089133
1085
121688
Y472
L
L
E
E
I
D
A
Y
N
R
A
K
C
S
G
Zebra Danio
Brachydanio rerio
Q9W6G6
764
87841
E181
L
L
H
S
N
T
M
E
S
G
R
M
K
C
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24322
850
95478
G267
R
L
N
C
S
I
P
G
D
Y
P
F
Y
F
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17330
712
78063
T129
G
V
S
L
V
C
G
T
H
A
F
S
P
K
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
97
N.A.
94.9
36.6
N.A.
N.A.
26.8
79.6
26.8
N.A.
29.5
N.A.
25.4
N.A.
Protein Similarity:
100
99.9
100
99.1
N.A.
97.4
51.3
N.A.
N.A.
40.2
89.4
40.2
N.A.
46.7
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
6.6
N.A.
N.A.
0
80
13.3
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
26.6
N.A.
N.A.
26.6
86.6
20
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
55
0
0
19
55
0
10
10
46
% A
% Cys:
10
0
0
10
0
10
0
0
0
0
0
0
55
10
10
% C
% Asp:
0
0
10
10
0
10
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
0
55
55
0
46
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
10
0
10
10
0
10
10
0
10
0
% F
% Gly:
10
10
0
0
0
0
10
10
0
10
0
0
0
0
10
% G
% His:
0
0
10
0
10
0
0
0
10
28
0
0
0
0
0
% H
% Ile:
0
0
0
0
55
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
55
10
10
0
% K
% Leu:
64
73
0
10
0
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
10
10
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
64
0
0
0
0
10
10
% N
% Pro:
10
10
0
0
10
0
10
10
0
10
10
0
10
0
10
% P
% Gln:
0
0
0
0
0
10
10
0
0
10
0
10
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% R
% Ser:
0
0
10
19
10
0
0
0
10
0
10
10
0
46
0
% S
% Thr:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
10
% T
% Val:
0
10
0
0
10
0
0
0
0
10
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
55
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _